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Public-ready7/3/2026

Vitamin E

Papers analyzed
131
Cholesterol and triglyceridesMale Reproductive Health MarkersBlood pressure and vascular health markers

Main benefit evidence

Review human evidence by goal.

Blood lipids
Cholesterol and triglycerides
Goal tierNot rated yet

No direct evidence for general supplement use is confirmed under the current standard.

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Men's health
Male Reproductive Health Markers
Goal tierNot rated yet

Direct evidence for general supplement use is currently limited under this standard.

1 human studies in a specific clinical context are available separately.

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Blood pressure and vascular health
Blood pressure and vascular health markers
Goal tierNot rated yet

The currently linked research coverage is not broad enough to characterize this goal yet.

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Side effects and combination findings in studies

Findings from studies of this ingredient alone are separated from findings involving another supplement or medication.

Caution signals
4
Side effects + combos + curated rules
Key precautions
No curated contraindication rule is available yet, but literature caution signals are shown below.
2 combo signals and 0 added-signal combos shown below.
These are signals reported in studies. They do not predict what will happen to an individual.

Findings to review with care

Side effects reported for the ingredient alone are separated from findings involving another supplement or medication.

Side effects reported when this ingredient was used alone

Symptoms or adverse events reported in studies of this ingredient without another active ingredient.

Adverse effect signal1 papers
High-dose vitamin E consumption was reported in three patients with cryptogenic intracerebral hemorrhage and acutely elevated serum alpha-tocopherol levels, suggesting an association between hypervitaminosis E and increased bleeding risk.Human studies · Study type not identified
Adverse effect signal1 papers
A statistically nonsignificant increased risk of prostate cancer was reported with vitamin E alone (RR = 1.13, P = 0.06).Human studies · Study type not identified

Caution signals when used with another supplement or medication

These studies reported a negative change, reduced absorption, or another caution when substances were used together. They do not predict an individual outcome.

와파린Vitamin E's anticoagulant effects amplify the risk of bleeding when combined with blood thinners like warfarin.
AspirinVitamin E's anticoagulant effects amplify the risk of bleeding when combined with blood thinners like aspirin.

Positive combinations studied

Positive combination findings are separated by how the study compared the groups. This is not a recommendation to combine them.

Positive findings when used together

The combination had a positive result, but the contribution of each ingredient could not be separated.

비타민 CIn a triple-blind RCT of 60 women with endometriosis, a combination of Vitamin C (1000 mg/day) and Vitamin E (800 IU/day) for 8 weeks significantly reduced pelvic pain, dysmenorrhea, and dyspareunia compared to placebo.
인삼The combined supplement significantly improved the desire domain of the FSFI compared to placebo.